Profile of children with cerebral palsy spectrum disorder and a normal MRI study.
Arielle SpringerSasha Dyck HolzingerJohn AndersenDavid BuckleyDarcy L FehlingsAdam KirtonLouise KoclasNicole PigeonEsias Van RensburgEllen WoodMaryam OskouiMichael ShevellPublished in: Neurology (2019)
Normal MRIs were associated with lack of perinatal adversity as well as with the dyskinetic, ataxic/hypotonic, and spastic diplegic CP subtypes. As MRI normality is not strongly associated with the severity of CP, continuous follow-up in children with normal imaging appears warranted. Further advanced imaging modalities, as well as strong consideration for metabolic and genetic testing, may provide additional insights into causal pathways in this population.