Systemic DPP4 activity is reduced during primary HIV-1 infection and is associated with intestinal RORC+ CD4+ cell levels: a surrogate marker candidate of HIV-induced intestinal damage.

Mickaël J PloquinArmanda CasrougeYoann MadecNicolas NoelBeatrice JacquelinNicolas HuotDarragh DuffySimon P JochemsLuca MicciCamille LécurouxFaroudy BoufassaThijs BooimanThalia Garcia-TellezMathilde GhislainRoger Le GrandOlivier LambotteNeeltje KootstraLaurence MeyerCecile GoujardMirko PaiardiniMatthew L AlbertMichaela Müller-Trutwin

Published in: Journal of the International AIDS Society (2019)

These data provide evidence that blood sDPP4 levels could be useful as a correlate for HIV-induced intestinal damage.

Keyphrases

antiretroviral therapy
hiv positive
hiv infected
human immunodeficiency virus
high glucose
diabetic rats
oxidative stress
hepatitis c virus
hiv testing
hiv aids
drug induced
single cell
electronic health record
endothelial cells
mesenchymal stem cells
machine learning
south africa
artificial intelligence