The Use of a Hypoallergenic Dermal Matrix for Wrapping in Peripheral Nerve Lesions Regeneration: Functional and Quantitative Morphological Analysis in an Experimental Animal Model.
Michele Rosario ColonnaAntonina FazioAlfio Luca CostaFranco GallettiRoberto Lo GiudiceBruno GallettiCosimo GallettiGiorgio Lo GiudiceGiovanni Dell'Aversana OrabonaIgor PapaliaGiulia RonchiStefano GeunaPublished in: BioMed research international (2019)
Histological and functional assessments show a functional recovery of the injured nerve in the test groups, stressed by the results of the grasping tests and the meaningful increasing in fiber diameter and higher g-ratio. Moreover, a connective tissue cuff distinguishes the distal portion of the injured nerve. Considering the easy availability and handling of the material used in this study we can conclude that this experimental technique can be considered as a valid alternative to protect nerves in nerve wrap surgery.