A plant-derived glucocorticoid receptor modulator with potency to attenuate the side effects of glucocorticoid therapy.

Yixuan WangJian GaoYing YuLin ZhouMiao WangWenwen XueBo LiuXudong WuXuefeng WuHuiyuan GaoYan ShenQiang Xu

Published in: British journal of pharmacology (2022)

Our results reveal that CA-e is a novel GR modulator with strong potency to attenuate the side effects of GC therapy and can be used as a potential molecular tool for deciphering GR signalling.

Keyphrases

genome wide
gene expression
stem cells
dna methylation
high resolution
single molecule
protein kinase
climate change
replacement therapy