Analysis of single-cell transcriptome data from a mouse model implicates protein synthesis dysfunction in schizophrenia.

Andrew E WellerThomas N FerraroGlenn A DoyleBenjamin C ReinerWade H BerrettiniRichard C Crist

Published in: Genes & genomics (2024)

Processes involving protein synthesis in general and the 'EIF2 Signaling' pathway in particular could be targets for the development of new research strategies and biomarkers in schizophrenia.

Keyphrases

single cell
bipolar disorder
rna seq
mouse model
signaling pathway
oxidative stress
electronic health record
high throughput
gene expression
pi k akt
epithelial mesenchymal transition
big data
genome wide
induced apoptosis
machine learning
cell proliferation
data analysis