ARAP2 inhibits Akt independently of its effects on focal adhesions.
Ruibai LuoPei-Wen ChenJean-Cheng KuoLisa JenkinsXiaoying JianClare M WatermanPaul A RandazzoPublished in: Biology of the cell (2018)
Our results highlight an Arf GAP-independent function of ARAP2 in regulating Akt activity and distinguish the effect of ARAP2 on Akt from that on FAs and integrin trafficking, which requires regulation of Arf6.