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Nuclear Condensation of CDYL Links Histone Crotonylation and Cystogenesis in Autosomal Dominant Polycystic Kidney Disease.

Lin DangXinyi CaoTianye ZhangYongzhan SunShanshan TianTianyu GongHui XiongPeipei CaoYuhao LiShengqiang YuLi YangLirong ZhangTong LiuKai ZhangJing LiangYupeng Chen
Published in: Journal of the American Society of Nephrology : JASN (2022)
These results elucidate a mechanism by which CDYL nuclear condensation links histone Kcr to transcriptional responses and cystogenesis in ADPKD.
Keyphrases
  • polycystic kidney disease
  • dna methylation
  • gene expression
  • transcription factor
  • heat shock
  • heat stress