Chronic abruption-oligohydramnios sequence (CAOS) revisited: possible implication of premature rupture of membranes.
Yoshitsugu ChigusaHaruta MogamiSachiko MinamiguchiAki KidoAyami IshidaYasuhisa KurataEriko YasudaKaoru KawasakiAkihito HorieKen YamaguchiMasaki MandaiEiji KondohPublished in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2021)
The fundamental cause of CAOS is repeated intrauterine hemorrhage and subsequent subchorionic hematoma, which induces hemorrhagic amniotic fluid and DCH. Consequently, these factors result in the necrosis and weakening of the amnion. Therefore, the true pathology of CAOS is believed to be premature rupture of membranes rather than chronic abruption.
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