A systematic review of the effects of transcutaneous auricular vagus nerve stimulation on baroreflex sensitivity and heart rate variability in healthy subjects.
Danesh SoltaniBayan AziziSepehr SimaKiarash TavakoliNegin Sadat Hosseini MohammadiAbdol-Hossein VahabieKaveh Akbarzadeh-SherbafAli Vasheghani FarahaniPublished in: Clinical autonomic research : official journal of the Clinical Autonomic Research Society (2023)
The results were mixed, which may be mainly attributable to the heterogeneity of the study designs and stimulation delivery dosages. Thus, future studies with comparable designs are required to determine the optimal stimulation parameters and clarify the significance of autonomic indices as a reliable marker of neuromodulation responsiveness.