Antibody to HSV gD peptide induced by vaccination does not protect against HSV-2 infection in HSV-2 seronegative women.
Peter B GilbertJean-Louis ExclerGeorgia D TomarasLindsay N CarppBarton F HaynesHua-Xin LiaoDavid C MontefioriSupachai Rerks-NgarmPunnee PitisuttithumSorachai NitayaphanJaranit KaewkungwalGustavo H KijakSodsai TovanabutraDonald P FrancisCarter LeeFaruk SinangilPhillip W BermanNakorn PremsriPrayura KunasolRobert J O'ConnellNelson L MichaelMerlin L RobbRhoda MorrowLawrence CoreyJerome H KimPublished in: PloS one (2017)
AIDSVAX® B/E containing gD did not confer protection from HSV-2 acquisition in HSV-2 seronegative women, despite eliciting anti-gD serum antibodies.