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Proanthocyanidins Antagonize Arsenic-Induced Oxidative Damage and Promote Arsenic Methylation through Activation of the Nrf2 Signaling Pathway.

Meng-Chuan XuQiang NiuYunhua HuGangling FengHaixia WangShu-Gang Li
Published in: Oxidative medicine and cellular longevity (2019)
GSPE activates the Nrf2 signaling pathway to antagonize As-induced oxidative damage and to promote As methylation metabolism. Therefore, GSPE may be a potential agent for relieving As-induced hepatotoxicity.
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