Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children.

Michael J Haller Helena Elding LarssonRoy N TamuraKendra VehikJoanna ClasenJay SosenkoWilliam A HagopianJin-Xiong SheAndrea K SteckMarian RewersOlli SimellJorma ToppariRiitta VeijolaAnette G ZieglerJeffrey P KrischerBeena AkolkarMichael J Hallernull null

Published in: Pediatric diabetes (2019)

This study highlights the application of precision medicine techniques to predict progression to diabetes over a 3-year window in TEDDY subjects. This multifaceted model provides preliminary improvement in prediction over simpler prediction tools. Additional tools are needed to maximize the predictive value of these approaches.

Keyphrases

type diabetes
glycemic control
cardiovascular disease
young adults
insulin resistance
metabolic syndrome
weight loss