The effects of hedgehog ligand neutralising antibody 5E1 in a mouse model of endometriosis.

Fiona L CousinsJ K FarleyR KerriganS MukherjeeS DarziC E GargettJ A Deane

Published in: BMC research notes (2020)

Treatment with 5E1 reduced the number of lesions found on the mesentery. No significant changes were found in the size of lesions, abundance of endometrial epithelial cells, proliferation or apoptosis.

Keyphrases

mouse model
oxidative stress
endoplasmic reticulum stress
signaling pathway
cell cycle arrest
endometrial cancer
combination therapy
cell proliferation
smoking cessation