Therapeutic Effect of IL-4 Receptor-Targeting Pro-Apoptotic Peptide (AP1-ELP-KLAK) in Glioblastoma Tumor Model.

Vijaya SarangthemAena YiYunjae KimAlnawaz RehemtullaByung-Heon LeeYoung Hyun JeonThoudam Debraj SinghRang-Woon Park

Published in: International journal of nanomedicine (2021)

Collectively, AP1-ELP-KLAK effectively induced cellular apoptosis of glioblastoma cells and non-invasive imaging provides a window for real-time monitoring of anti-tumor effect with the provision of improving therapeutic efficacy in a glioblastoma mice model.

Keyphrases

cell cycle arrest
cell death
induced apoptosis
transcription factor
endoplasmic reticulum stress
oxidative stress
high resolution
diabetic rats
anti inflammatory
pi k akt
type diabetes
drug delivery
adipose tissue
high fat diet induced
drug induced
signaling pathway
endothelial cells
stress induced