Epigenetic mechanisms of rapid-acting antidepressants.

Antonio Inserra Antonella CampanaleTamim RezaiPatrizia Romualdi Tiziana Rubino

Published in: Translational psychiatry (2024)

Correlative evidence suggests that epigenetic changes induced by RAADs accompany therapeutic and side effects, although causation, mechanisms, and cell type-specificity remain largely unknown. Addressing these research gaps may lead to the development of novel neuroepigenetics-based precision therapeutics.

Keyphrases

dna methylation
gene expression
major depressive disorder
small molecule
loop mediated isothermal amplification
structural basis