Disrupted BMP-9 Signaling Impairs Pulmonary Vascular Integrity in Hepatopulmonary Syndrome.
Fabien RobertMarie-Caroline CertainAudrey BaronRaphaël ThuilletLéa DuhautMina OttavianiMustapha Kamel ChelghamCorinne NormandNihel BerrebehNicolas RicardValerie FurlanAgnès Desroches-CastanEmmanuel GonzalesEmmanuel JacqueminOlivier SitbonMarc HumbertSabine BaillyAudrey CoillyChristophe GuignabertLy TuLaurent SavalePublished in: American journal of respiratory and critical care medicine (2024)
The study findings suggest that portal hypertension-induced loss of BMP-9 signaling contributes to HPS development.