Influence of household pet ownership and filaggrin loss-of-function mutations on eczema prevalence in children: A birth cohort study.
Kenji ToyokuniKiwako Yamamoto-HanadaLimin YangKouhei HaginoDaisuke HaramaMarei OmoriYasuaki MatsumotoDaichi SuzukiKotaro UmezawaKazuma TakadaMami ShimadaSeiko HiraiFumi IshikawaSayaka HamaguchiMayako Saito-AbeMiori SatoYumiko MiyajiShigenori KabashimaTatsuki FukuieEmiko NoguchiKohta SuzukiYukihiro OhyaPublished in: Allergology international : official journal of the Japanese Society of Allergology (2024)
Household dog and pet (dog, cat, or both) ownership was protective against early childhood eczema in a birth cohort dataset. This protective association was observed only in children without FLG mutations, which should be confirmed in studies with larger cohorts.