Exaggerated myocardial torsion may contribute to dynamic left ventricular outflow tract obstruction in hypertrophic cardiomyopathy.

Ada K C LoThomas MewChristina MewKristyan Guppy-ColesArun DahiyaArnold NgSandhir B Prasad John J Atherton

Published in: European heart journal open (2023)

This study demonstrates that increased peak LV twist is independently associated with LVOTO in patients with HCM. Peak twist was similarly exaggerated in patients with only latent LVOTO, suggesting that it may play a contributory role to LVOTO in HCM.

Keyphrases

hypertrophic cardiomyopathy
left ventricular
epithelial mesenchymal transition
cardiac resynchronization therapy
heart failure
acute myocardial infarction
left atrial
aortic stenosis
mitral valve
coronary artery disease
acute coronary syndrome
signaling pathway
atrial fibrillation
aortic valve
ejection fraction