Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population.

Niels GrarupIda MoltkeMette K AndersenPeter BjerregaardChristina V L LarsenInger K Dahl-PetersenEmil JørsboeHemant K TiwariScarlett E HopkinsHoward W WienerBert B BoyerAllan LinnebergOluf PedersenMarit E JørgensenAnders AlbrechtsenTorben Hansen

Published in: Diabetologia (2018)

The Greenlandic MetaboChip-genotype data are available at European Genome-Phenome Archive (EGA; https://ega-archive.org/ ) under the accession EGAS00001002641.

Keyphrases

type diabetes
copy number
electronic health record
glycemic control
cardiovascular disease
genome wide
big data
insulin resistance
gene expression
dna methylation
metabolic syndrome
machine learning
skeletal muscle
weight loss