Longitudinal analysis at pre- and post-flare of T peripheral helper and T follicular helper subsets in patients with systemic lupus erythematosus.

Noriyasu SekiHideto TsujimotoShuhei TanemuraJun KikuchiShuntaro SaitoKunio SugaharaKeiko YoshimotoMitsuhiro AkiyamaTsutomu TakeuchiKenji ChibaYuko Kaneko

Published in: Immunology letters (2024)

Increased frequency of Tph1 and Tph2 subsets and elevated levels of serum IFN-λ1 are presumably critical for triggering of flare in SLE.

Keyphrases

dendritic cells
regulatory t cells
peripheral blood
systemic lupus erythematosus
immune response
disease activity
chemotherapy induced
data analysis