Structural Characterisation of Non-Deamidated Acidic Variants of Erwinia chrysanthemi L-asparaginase Using Small-Angle X-ray Scattering and Ion-Mobility Mass Spectrometry.
David GervaisDarryl KingPatrick KandaNicholas FooteLucy ElliottPhillip BrownNatacha O LeeKonstantinos ThalassinosClaire PizzeyRobert RamboThomas C MinshullMark J DickmanStuart SmithPublished in: Pharmaceutical research (2015)
IEX data for biopharmaceuticals such as ErA should be thoroughly characterised, as the most common modifications, such as deamidation, may be absent.