Energetic cost of walking and Brain Atrophy in Mid-to-Late Life.
Ryan DoughertyFangyu LiuYang AnAmal Asiri WanigatungaQu TianChristos DavatzikosEleanor M SimonsickLuigi FerruciSusan M ResnickJennifer A SchrackPublished in: The journals of gerontology. Series A, Biological sciences and medical sciences (2021)
The energetic cost of walking is associated with gray and white matter volumes and subsequent hippocampal atrophy and ventricular enlargement. Collectively, these data suggest the energetic cost of walking may be an early marker of neurodegeneration that contributes to the gait brain connection.