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WNT16 elevation induced cell senescence of osteoblasts in ankylosing spondylitis.

Sungsin JoSubin WeonBora NamMi-Ae JangHyundeok KangTae-Jong KimYe-Soo ParkTae Hwan Kim
Published in: Arthritis research & therapy (2021)
WNT16 is highly expressed in AS and WNT16 treatment facilitated cell senescence in AS-osteoprogenitor cells during osteoblast differentiation accompanied by suppression of bone formation. The identified role of WNT16 in AS could influence bone loss in AS patients.
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