Relationship between neuropsychiatric disorders and cognitive and behavioural change in MND.
Caroline A McHutchisonDanielle Jane LeightonAndrew McIntoshElaine ClearyJon WarnerMary PorteousSiddharthan ChandranSuvankar PalSharon AbrahamsPublished in: Journal of neurology, neurosurgery, and psychiatry (2019)
Neuropsychiatric disorders in patients and their families are associated with cognitive and behavioural changes post-MND diagnosis, with many occurring independently of MND-FTD and C9orf72 status. These findings support an overlap between MND, frontotemporal dementia and neuropsychiatric disorders, particularly mood disorders.