Meprin β metalloproteases associated with differential metabolite profiles in the plasma and urine of mice with type 1 diabetes and diabetic nephropathy.

Jessica GoodingLei CaoCourtney WhitakerJean-Marie MwizaMizpha FernanderFaihaa AhmedZach AcuffSusan McRitchieSusan SumnerElimelda Moige Ongeri

Published in: BMC nephrology (2019)

Taken together, the annotated metabolites suggest that meprin β impacts complications of diabetes such as DKD by altering distinct metabolite profiles.

Keyphrases

diabetic nephropathy
type diabetes
cardiovascular disease
ms ms
glycemic control
risk factors
high fat diet induced
metabolic syndrome
skeletal muscle
weight loss