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Analysis of pathogenic variants in BRCA1 and BRCA2 genes using next-generation sequencing in women with triple negative breast cancer from South India.

Taruna RajagopalArun SeshachalamArunachalam JothiKrishna Kumar RathnamSrikanth TalluriSivaramakrishnan VenkatabalasubranianNageswara Rao Dunna
Published in: Molecular biology reports (2022)
Our data advocates that South Indian women with higher grade TNBC tumors and without HBOC could be considered for BRCA mutation screening, thereby enabling enhanced decision-making and preventive therapy.
Keyphrases
  • decision making
  • copy number
  • breast cancer risk
  • genome wide
  • electronic health record
  • stem cells
  • dna methylation
  • bioinformatics analysis
  • circulating tumor
  • genome wide identification
  • genome wide analysis