Quality evaluation of gentamicin sulfate reference standards in Japanese Pharmacopoeia using hydrophilic interaction chromatography combined with tandem mass spectrometry.
Keiko MaekawaRyuichi SawaMari MatsuiToshifumi KondaYumiko KubotaAyaka MatsuoAkiho MaedaChisato TakahashiTsuyoshi TanimotoYukari NakagawaSachiyo YonedaYuri MoriSatowa SuzukiPublished in: Journal of AOAC International (2023)
Novel analytical procedures useful for routine quality control of GmS were developed using HILIC-MS/MS.
Keyphrases
- liquid chromatography
- tandem mass spectrometry
- quality control
- ultra high performance liquid chromatography
- high performance liquid chromatography
- mass spectrometry
- ms ms
- high resolution mass spectrometry
- simultaneous determination
- gas chromatography
- solid phase extraction
- liquid chromatography tandem mass spectrometry
- clinical practice
- quality improvement
- high resolution
- high speed