Prognostic significance of a comprehensive histological evaluation of reticulin fibrosis, collagen deposition and osteosclerosis in primary myelofibrosis patients.

Umberto GianelliStefano FioriDaniele CattaneoAnna BossiIvan CortinovisArturo BonomettiGiulia ErcoliCristina BucelliNicola OrofinoGaetano BulfamanteAlessandra Iurlo

Published in: Histopathology (2017)

The comprehensive RCO score, obtained by histological evaluation of reticulin fibrosis, collagen deposition and osteosclerosis was prognostically significant and more accurate than ECGMF grade in identifying high-risk patients and improved PPV when applied in addition to IPSS.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
peritoneal dialysis
patient reported outcomes