Antimalarial Activity of Hydromethanolic Crude Extract and Chloroform Fraction of Brucea antidysenterica Leaves in Plasmodium berghei-Infected Mice.

Tezera Jemere Aragaw Kefyalew Ayalew Getahun

Published in: Evidence-based complementary and alternative medicine : eCAM (2021)

From our study, it is concluded that the hydromethanolic crude extract and chloroform fraction of B. antidysenterica leaves showed promising antiplasmodial effects against Plasmodium berghei. This upholds the folkloric use of B. antidysenterica leaves and the thought of as a possible source to develop new antimalarial agents.

Keyphrases

plasmodium falciparum
oxidative stress
essential oil
high fat diet induced
type diabetes
metabolic syndrome
insulin resistance
skeletal muscle