Moderate to severe acute pain disturbs motor cortex intracortical inhibition and facilitation in orthopedic trauma patients: A TMS study.
Marianne JodoinDominique M RouleauAudrey BellemareCatherine ProvostCamille Larson-DupuisÉmilie SandmanGeorges-Yves LaflammeBenoit BenoitStéphane LeducMartine LevesqueNadia GosselinLouis De BeaumontPublished in: PloS one (2020)
These findings show altered M1 in the context of acute moderate to severe pain, suggesting early signs of altered GABAergic inhibitory and glutamatergic facilitatory activities.