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Multidimensional Analysis of Lung Lymph Nodes in a Mouse Model of Allergic Lung Inflammation following P M 2.5 and Indeno[1,2,3- cd ]pyrene Exposure.

Kwei-Yan LiuYajing GaoWenfeng XiaoJinrong FuSaihua HuangXiao HanShih-Hsien HsuXiaojun XiaoShau-Ku HuangYufeng Zhou
Published in: Environmental health perspectives (2023)
(IP)-AhR-c-Maf axis in Tfh2 cells was important in allergen sensitization and lung inflammation, thus adding a new dimension in the understanding of Tfh2 cell differentiation and function and providing a basis for establishing the environment-disease causal relationship. https://doi.org/10.1289/EHP11580.
Keyphrases
  • mouse model
  • oxidative stress
  • lymph node
  • induced apoptosis
  • endoplasmic reticulum stress
  • allergic rhinitis
  • cell death
  • neoadjuvant chemotherapy