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A biosafety level-2 dose-dependent lethal mouse model of spotted fever rickettsiosis: Rickettsia parkeri Atlantic Rainforest strain.

Andres F LondoñoNicole L MendellDavid H WalkerDonald H Bouyer
Published in: PLoS neglected tropical diseases (2019)
Since R. parkeri is used at biosafety level 2, the greatest advantage of this inbred mouse model is the ability to investigate immunity and pathogenesis of rickettsiosis with all the tools available at biosafety level 2.
Keyphrases
  • mouse model