Evaluation of the inflammatory markers CCL8, CXCL5, and LIF in patients with anastomotic leakage after colorectal cancer surgery.

Fee KluppS SchulerC KahlertN HalamaC FranzP MayerT SchmidtA Ulrich

Published in: International journal of colorectal disease (2020)

Measurement 3 days after surgery revealed altered protein expression patterns of the inflammatory markers CCL8/MCP2, LIF, and CXCL5/ENA-78 in peritoneal fluid from patients developing anastomotic leakage after colorectal surgery. Further studies with a larger patient cohort with inclusion of different variables are needed to evaluate their potential as predictive biomarkers for anastomotic leakage.

Keyphrases

rectal cancer
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
minimally invasive
liver fibrosis
prognostic factors
peritoneal dialysis
single cell
atrial fibrillation
case control
coronary artery disease
risk assessment
patient reported