Opioid-induced constipation: a stepwise treatment algorithm feasibility study.
Andrew Neil DaviesCharlotte LeachClaire ButlerShuchita Dhwiren PatelKate ShorthoseKabir BatsariPublished in: BMJ supportive & palliative care (2021)
The feasibility study suggests that a definitive study can be successfully completed. However, we will amend the methodology to try to improve participant recruitment, participant retention and adherence to the treatment algorithm. The feasibility study also suggests that the use of the BFI to monitor OIC, and the use of a treatment algorithm to manage OIC, can result in clinically important improvements in OIC.Trial registration numberNCT04404933.