Clinical implications of increased uptake in bone marrow and spleen on FDG-PET in patients with bacteremia.
Jordy P PijlThomas C KweeRiemer H J A SlartDerya YakarMarjan Wouthuyzen-BakkerAndor W J M GlaudemansPublished in: European journal of nuclear medicine and molecular imaging (2020)
High FDG uptake in the bone marrow is associated with a higher inflammatory response and younger age in patients with bacteremia. In patients with high FDG uptake in the bone marrow, a cardiovascular or musculoskeletal focus of infection is more likely than other foci, and the infection is more often caused by Gram-negative species. High splenic FDG uptake is associated with a higher inflammatory response as well, and a cardiovascular focus of infection is also more likely in case of high splenic FDG uptake.