Characterization of the nigroestriatal system in a sample of patients with amyotrophic lateral sclerosis.
Claudio Alejandro Jimenez MonsalveLuis Henrique Tieppo FornariNeivo da Silva JúniorDouglas Tomio NakataEurípedes Gomes de Carvalho NetoFrancisco Tellechea RottaCarlos Roberto de Mello RiederPublished in: Arquivos de neuro-psiquiatria (2022)
Our study fits with the neuropathological and functional evidence that demonstrates the existence of nigrostriatal dysfunction in patients with ALS. Further research to better understand the role of these changes in the pathophysiological process of ALS needs to be performed.