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Detection of SARS-CoV-2 Nucleocapsid and Microvascular Disease in the Brain: A Case Report.

Catherine DeMarinoMyoung-Hwa LeeMaria CowenJoseph P SteinerSara InatiAshish H ShahKareem A ZaghloulAvindra Nath
Published in: Neurology (2022)
Despite the lack of evidence of viral replication within the brain, the presence of the nucleocapsid protein was associated with disease-specific endothelial cell activation, fibrinogen leakage, and immune cell infiltration.
Keyphrases
  • sars cov
  • respiratory syndrome coronavirus
  • white matter
  • resting state
  • endothelial cells
  • cerebral ischemia
  • multiple sclerosis
  • binding protein
  • brain injury
  • blood brain barrier
  • high glucose