Discordance between original and central laboratories in ER and HER2 results in a diverse, population-based sample.
Jennifer J GriggsAnn S HamiltonKendra L SchwartzWeiqiang ZhaoPaul H AbrahamseDafydd G ThomasJulie M JornsRachel JewellMaria E Sibug SaberReina HaqueSteven J KatzPublished in: Breast cancer research and treatment (2016)
Discordance between original and central laboratories in two large metropolitan areas was low in this population-based sample compared to previously reported patient samples. Centralization of testing for key pathology variables appears to be occurring in many hospitals. In addition, quality improvement efforts may have preceded the publication and dissemination of specialty society guidelines.