Dynamics of alternative splicing during somatic cell reprogramming reveals functions for RNA-binding proteins CPSF3, hnRNP UL1, and TIA1.

Claudia Vivori Panagiotis Papasaikas Ralph Stadhouders Bruno Di Stefano Anna Ribó RubioClara Berenguer BalaguerSerena F Generoso Anna Mallol José Luis Sardina Bernhard Payer Thomas Graf Juan Valcárcel

Published in: Genome biology (2021)

Our results reveal common programs of splicing regulation during reprogramming of different cell types and identify three novel regulators of this process and their targets.

Keyphrases

single cell
cell therapy
public health
genome wide
transcription factor
copy number
mesenchymal stem cells
gene expression
bone marrow