TSPAN18 facilitates bone metastasis of prostate cancer by protecting STIM1 from TRIM32-mediated ubiquitination.

Qianghua ZhouXu ChenKai YaoYangjie ZhangHaixia HeHao HuangHao ChenShengmeng PengMing HuangLiang ChengQiang ZhangRuihui XieKaiwen LiTianxin LinHai Huang

Published in: Journal of experimental & clinical cancer research : CR (2023)

signaling axis, suggesting that TSPAN18 may be an attractive therapeutic target for blocking bone metastasis in PCa.

Keyphrases

prostate cancer
bone mineral density
soft tissue
bone loss
radical prostatectomy
bone regeneration
postmenopausal women
body composition