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Icaritin, an inhibitor of beta-site amyloid cleaving enzyme-1, inhibits secretion of amyloid precursor protein in APP-PS1-HEK293 cells by impeding the amyloidogenic pathway.

Fei FengYuanyuan LiNanqu HuangYong Luo
Published in: PeerJ (2019)
Icaritin, as a BACE1 inhibitor, inhibits APP secretion in APP-PS1-HEK293 cells by impeding the amyloidogenic pathway.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • cell death
  • signaling pathway
  • binding protein
  • protein protein