Login / Signup

Identification of uncommon oral yeasts from cancer patients by MALDI-TOF mass spectrometry.

Narges AslaniGhasem JanbabaeiMahdi AbastabarJacques F MeisMahasti BabaeianSadegh KhodavaisyTeun BoekhoutHamid Badali
Published in: BMC infectious diseases (2018)
This current study provides insight into the prevalence and susceptibility profiles of Candida species, including emerging Candida species and uncommon yeasts, isolated from the oral cavity of Iranian cancer patients. The incidence of oral candidiasis was higher amongst patients with hematological malignancies. The majority of oral infections were caused by non-albicans Candida species which were often more resistant to anti-fungal agents. Our findings suggest that anidulafungin should be used as antifungal of choice for prophylaxis in clinically high-risk patients with documented oral colonization or infection.
Keyphrases
  • candida albicans
  • mass spectrometry
  • biofilm formation
  • risk factors
  • liquid chromatography
  • gas chromatography
  • high resolution
  • high performance liquid chromatography
  • cystic fibrosis