Amelioration of 5-Fluorouracil Induced Nephrotoxicity by Acacia catechu through Overcoming Oxidative Damage and Inflammation in Wistar Rats.

Gayatri Jaising Gadekar Pranali Anandrao Bhandare Deepti Dinesh Bandawane

Published in: Cardiovascular & hematological disorders drug targets (2023)

The ethyl acetate fraction of A. catechu leaves exhibited a mitigating influence on the renal impairment caused by 5-FU, showcasing its potential as a nephroprotective agent capable of preventing and ameliorating 5-FU-induced nephrotoxicity.

Keyphrases

drug induced
high glucose
diabetic rats
oxidative stress
endothelial cells