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Usefulness of point-of-care multiplex PCR to rapidly identify pathogens responsible for ventilator-associated pneumonia and their resistance to antibiotics: an observational study.

Charles-Edouard LuytGuillaume HékimianIsabelle BonnetNicolas BréchotMatthieu SchmidtJérôme RobertAlain CombesAlexandra Aubry
Published in: Critical care (London, England) (2020)
Compared to conventional microbiological cultures, the Unyvero pneumonia cartridge had poor diagnostic performance: it correctly identified pathogens and their resistance mechanisms in 73% and 67% of VAP cases, respectively. The lack of performance on the resistance mechanism was more pronounced when the pathogen detected was a Pseudomonas aeruginosa.
Keyphrases
  • pseudomonas aeruginosa
  • gram negative
  • cystic fibrosis
  • antimicrobial resistance
  • high throughput
  • candida albicans
  • real time pcr
  • multidrug resistant
  • escherichia coli
  • drug resistant
  • intensive care unit