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Nanopore sequencing method for CTG18.1 expansion in TCF4 in late-onset Fuchs endothelial corneal dystrophy and a comparison of the structural features of cornea with first-degree relatives.

Gozde Sahin VuralHilmi Bolat
Published in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2023)
A strong association between the corneal endothelium in relatives and TNR number of FCEDs was defined. Relatives tended to have fewer corneal endothelial cells, even though they did not have clinical findings.
Keyphrases
  • late onset
  • endothelial cells
  • early onset
  • optical coherence tomography
  • wound healing
  • cataract surgery
  • nitric oxide
  • vascular endothelial growth factor