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Genotype Analysis of Clinical Candida albicans Isolates Using PCRs Targeting 25S rDNA and ALT Repeat Sequences of the RPS and Antifungal Susceptibility in Ouagadougou (Burkina Faso).

Patindoilba Marcel SawadogoAdama ZidaIssiaka SoulamaS Samuel SerméKiswendsida Thierry GuiguemdéRichard JuniorIbrahim SangareSanata BambaRasmata Ouédraogo-TraoréTinga Robert Guiguemdé
Published in: Infection and drug resistance (2019)
Our study showed that Candida albicans resistance to azoles, especially to fluconazole, is an important phenomenon in Ouagadougou, and several genotypes RPS types are involved. Thus, fluconazole would not be an antifungal agent for first-line prescribing for treatment of candidiasis in Ouagadougou. This study will be continued to determine the molecular mechanisms involved in these antifungal resistances, for further research of new molecules with different action targets.
Keyphrases
  • candida albicans
  • biofilm formation
  • primary care
  • drug delivery
  • replacement therapy