Prognostic Significance of Thrombomodulin mRNA in High-Grade Soft Tissue Sarcomas after 10 years.

Kunihiro AsanumaTomoki NakamuraYumiko AsanumaTakayuki OkamotoTakuya KakimotoYuki YadaTomohito HagiKouji KitaKoichi NakamuraAkihiko MatsumineAkihiro Sudo

Published in: Orthopaedic surgery (2020)

High levels of TM mRNA may be a significant predictor of recurrence, metastasis, and a poor outcome in STS patients after 10 years. TM is a candidate molecular marker and may be clinically useful for devising a therapeutic treatment strategy by prediction of prognosis.

Keyphrases

high grade
soft tissue
end stage renal disease
ejection fraction
newly diagnosed
low grade
prognostic factors
binding protein
patient reported outcomes
combination therapy