First non-invasive magnetic phrenic nerve and diaphragm stimulation in anaesthetized patients: a proof-of-concept study.
Alessandro PanelliHermann Georges BartelsSven KrauseMichael André VerfußAline Michèle GrimmNiklas Martin CarbonJulius J GrunowDiego StutzerThomas NiederhauserLaurent BrochardSteffen Weber-CarstensStefan J SchallerPublished in: Intensive care medicine experimental (2023)
Bilateral non-invasive electromagnetic phrenic nerve stimulation generated a tidal volume of 3-6 ml/kg ideal body weight due to diaphragmatic contraction in lung-healthy anaesthetized patients. Further perspectives in critically ill patients should include assessment of clinical outcomes to confirm whether diaphragm contraction through non-invasive electromagnetic phrenic nerve stimulation potentially ameliorates or prevents diaphragm atrophy.
Keyphrases
- end stage renal disease
- body weight
- ejection fraction
- newly diagnosed
- chronic kidney disease
- mechanical ventilation
- prognostic factors
- mouse model
- intensive care unit
- patient reported outcomes
- high frequency
- mass spectrometry
- extracorporeal membrane oxygenation
- high resolution
- patient reported
- liquid chromatography
- tandem mass spectrometry