Login / Signup

Beta-adrenergic blockade increases pulmonary vascular resistance and causes exaggerated hypoxic pulmonary vasoconstriction at high altitude: a physiological study.

Matthias Peter HiltyChristoph SiebenmannPeter RasmussenStefanie KeiserAndrea MüllerCarsten LundbyMarco Maggiorini
Published in: European heart journal. Cardiovascular pharmacotherapy (2024)
Our data show that beta-adrenergic blockade increases, and muscarinic blockade decreases PVR, whereas both increase pulmonary artery elastance. Future studies may confirm potential implications from the finding that beta-adrenergic blockade exaggerates HPV for the management of mountaineers using beta-blockers for prevention or treatment of cardiovascular conditions.
Keyphrases
  • pulmonary artery
  • pulmonary hypertension
  • coronary artery
  • pulmonary arterial hypertension
  • electronic health record
  • current status
  • deep learning
  • case control
  • combination therapy
  • replacement therapy