Patient-specific genetic factors predict treatment failure in sofosbuvir-treated patients with chronic hepatitis C.

Catrina M LoucksJennifer J LinJessica N TruemanBritt I DrögemöllerGalen E B WrightWan-Chun ChangKathy H LiEric M YoshidaJo-Ann FordSamuel S LeePam CrottyRichard B KimBandar Al-JudaibiUte I SchwarzAlnoor RamjiJeanette F FarivarEdward TamLori Lee WalstonColin J D RossBruce C Carleton

Published in: Liver international : official journal of the International Association for the Study of the Liver (2022)

Ultimately, this work demonstrates that patient-specific genetic factors could be used as a tool to identify patients at higher risk of treatment failure and allow for these patients to receive effective therapy sooner.

Keyphrases

end stage renal disease
newly diagnosed
chronic kidney disease
stem cells
gene expression
copy number
combination therapy
mesenchymal stem cells